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Privacy Policy

Genentech, Inc. ("Genentech") respects the privacy of our consumers and visitors to this website. We have established this Privacy Policy so that you are informed about how we treat any personal information that you provide to us in the course of using this website or that we may otherwise collect from or about you in connection with our products and services. In the United States, Genentech and Blueprint Medicines Corporation (“Blueprint”) work together to develop and co-promote Gavreto. However, this website is solely owned and operated by Genentech, and the personally identifiable information you share through this website is collected directly by Genentech. This Policy describes Genentech’s information handling practices, as Genentech operates this website. On this website, certain information may be shared, where applicable, with Blueprint. Once that information has been shared with Blueprint, your information will be governed by Blueprint’s Privacy Policy found here

This Privacy Policy will inform you of:

  • How you will be informed of updates to this Privacy Policy;
  • What personally identifiable information of yours we may collect from you through our website and how we may use this information;
  • Limits on how we would share and disclose your personally identifiable information;
  • Our policy regarding collection of personally identifiable information from minors;
  • How our website uses cookies and similar technologies;
  • Our practices concerning retargeting and interest-based advertising;
  • Our policy regarding browser "do not track" signals;
  • How our website uses social media plugins;
  • Our policy regarding links to third party websites;
  • Security of our website;
  • Additional information for California residents; and
  • How you can correct and update your personally identifiable information.

Please note that this Genentech website is directed towards users who reside in the United States of America ("U.S."). It is not our intent to gather personally identifiable information from individuals residing outside the U.S. Your access to and use of this website constitutes acceptance of this Privacy Policy and consent to Genentech's collection and use of your information, as outlined below.

Privacy Policy Updates

From time to time, Genentech may revise this Privacy Policy. Any such changes to this Privacy Policy will be promptly reflected on this page. Genentech encourages you to review this Privacy Policy regularly for any changes. Your continued use of this website will be subject to the then-current Privacy Policy. The effective date of this Privacy Policy is July 1, 2021.

Information Collection and Use

You can generally visit our website without revealing any personally identifiable information about yourself. However, to access certain options and services we may ask you to provide certain personally identifiable information and without providing such personally identifiable information, you may be unable to access certain options and services. The following is personally identifiable information that you may voluntarily provide to us and how we use it:

  • Surveys. Information obtained from you on web surveys, such as contact information (name and shipping address), demographic information (zip code, age level) and medical condition. We may use this personally identifiable information to provide you with information and services for which you have expressed an interest or that you may find useful based on your answers in a survey. Additionally, we may refer to your personally identifiable information to better understand your needs and how we can improve our website.
  • Newsletters. Information obtained from you from your request to subscribe to a newsletter, such as contact information (name and email address). We may use this personally identifiable information to deliver the newsletters that you have elected to receive.
  • Registration. Information obtained from you on registration forms used to process your requests for services and information or to participate in our programs, such as contact information (name, address, email address), password, username or code, age, date of birth, gender, ethnicity and medical condition. This registration information may also be gathered if you register for certain services via phone, fax or mail. We may use this information to send you a welcoming email to verify your username and password, website updates, special offers, notices regarding relevant medical conditions and treatment, or other information responsive to the data that you provide to us. Additionally, we may refer to your personally identifiable information to better understand your needs and how we can improve our website.
  • Email Content to a Friend. Information obtained from you regarding friend or family name and email address, if you elect to use our referral service for sending some of our website content to friends and family. We may use this personally identifiable information to automatically send the friend or family member a one-time email inviting them to visit the website. We may store this information for the sole purpose of sending this one-time email.
  • Other Modes of Collection. Information we collect from or about you in other online or offline contexts, including information submitted during purchases of our GAVRETO® products, interactions with Genentech employees, adverse event reporting, or participation in a research study. We use such information for a variety of purposes.

We may combine the personally identifiable information you share with us through our website with other information we collect from or about you, both online and offline. We may also combine this personally identifiable information with records provided by third parties. We use this consolidated information to help us better design our products, to communicate information to you, to enhance our marketing and research activities, and to facilitate other business functions.

In addition to the purposes described above, any information we collect may also be used for analytics purposes (e.g., evaluating site usage patterns, assessing throughput) so that we can gauge the effectiveness of our programs and improve the usefulness of information presented to users.

Sharing and Disclosure

We may provide your personally identifiable information that we collect and the data generated by cookies (discussed below) to a parent, subsidiary or affiliate entity within the Genentech corporate families, partner entities, and the vendors and service agencies that we may engage to assist us. For example, we may provide your personally identifiable information to an organization in order to complete a service (e.g., send out newsletter emails you have requested) to assist us in reviewing the data or to provide marketing or advertising on our behalf.

We will also disclose your personally identifiable information if we reasonably believe we are required to do so by law, regulation, legal process, or other government authority (such as reporting safety information to the Food and Drug Administration); to investigate fraud; to protect your safety or the safety of others; or when we have reason to believe that disclosing this information is necessary to protect our rights or the rights of a third party who may be harmed by your activities.

We may transfer your personally identifiable information to a successor entity of Genentech upon a merger, consolidation or other corporate reorganization in which Genentech participates or to a purchaser of all or a portion of Genentech's assets; or pursuant to a financing arrangement or co-promotional agreement. Any successor entity shall be bound by terms and conditions reasonably similar to this Privacy Policy.


This website is not intended for or designed to attract children under the age of 13. Moreover, we do not knowingly collect any personally identifiable information from anyone under the age of 18 without the consent of a parent or guardian, and you must be 18 years of age or older to submit registration or survey information. Should you believe that a minor of whom you are a parent or guardian has registered, please contact us at [email protected] and we will make reasonable efforts to remove all personally identifiable information related to the minor.

Cookies, LSOs, GIF Files, and Other Tracking Technologies

This website may use cookies, local shared objects (LSOs) and other tracking technologies to identify users who have previously visited so the user is recognized upon return, thereby saving them time while on our website. A cookie is a piece of data stored on the user's hard drive containing information about the user. If a user rejects the cookie, they may still use our website. A cookie may be placed by us, or by vendors or service agencies who work with us or with our partners. Similar to a cookie, a Local Shared Object is a collection of data that a web site running Adobe Flash can place on your hard drive to recognize a repeat visitor and store settings and other information.

Our website and emails we send to you may contain transparent GIF files (also known as "web beacons," "action tags," or "pixel tags") to help manage online advertising.

These GIF files are used by us and our ad management partners to recognize when a visitor views a web page or opens an email. This information enables us to learn which emails and advertisements bring users to our website.

If you have provided us with personally identifiable information, e.g., through a registration or a request for certain materials, we may associate this personally identifiable information with information gathered through these tracking technologies. This allows us to offer increased personalization and functionality.

This website may use Google Analytics, a web analytics service provided by Google, Inc. ("Google"). Google Analytics uses cookies to analyze use patterns and may collect information about your use of the website, including your IP address. More information on Google Analytics can be found here: If you would like to opt-out of having your data used by Google Analytics, please use the Google Analytics opt-out available here: Other information on opt-outs for targeted advertisement delivery is available below. Please note that Genentech makes no representations regarding the functionality of Google opt-out mechanisms, and further, opting out of Google Analytics will not preclude the use of your data by other analytics services.

Retargeting and Interest-Based Advertising

We use third party advertising companies to place ads on other websites. These companies may use data about your visits to this and other websites in order to measure advertising effectiveness and to provide advertisements about our goods and services that may be of interest to you. Like most advertisers, we place advertisements where we think they will be most relevant to customers. One way we do so is by allowing network advertising companies with whom we work to place their own cookies when an individual visits our site. This enables the network advertising company to recognize individuals who have previously visited our site. When the individual visits a third-party web site on which that network advertising company has purchased ad space, the advertising company can then recognize the individual’s interest in our products and services and deliver one of our advertisements.

Some of our websites use two Google Analytics Advertising Display Features, which collect information through cookies: Remarketing with Google Analytics and Demographics and Interests reporting. If you would like to opt-out of having your data used by these cookies, please use the Google Analytics opt-out available here:

The Digital Advertising Alliance maintains a web site where consumers can opt out from receiving interest-based advertising from some or all of the network advertising companies participating in the program (

Do-Not-Track Signals and Similar Mechanisms

Some web browsers may transmit "do-not-track" signals to websites with which the browser communicates. This website does not currently respond to these "do-not- track" signals.

Social Media Plugins

Our website may use social media plugins (e.g., the Facebook "Like" button, "Share to Twitter" button) to enable you to easily share information with others. When you visit our website, the operator of the social plugin can place a cookie on your computer, enabling that operator to recognize individuals who have previously visited our site. If you are logged into the social media website (e.g., Facebook, Twitter, Google+) while browsing on our website, the social plugins allow that social media website to receive information that you have visited our website. The social plugins also allow the social media website to share information about your activities on our website with other users of their social media website. For example, Facebook Social Plugins allows Facebook to show your Likes and comments on our pages to your Facebook friends. Facebook Social Plugins also allow you to see your friends' Facebook activity on our website. Genentech does not control any of the content from the social media plugins. For more information about social plugins from other social media websites you should refer to those sites' privacy and data sharing statements.

Log Files and Aggregate Information

We may track the total number of visitors to our website, the number of visitors to each page of our website, IP addresses, and the domain names of our users' Internet Service Providers, and we may analyze these data for trends and statistics in the aggregate, but such information will be in aggregate form only and it will not contain personally identifiable data. Such aggregate information is not linked to any personally identifiable information that can identify any individual person.

We may use such aggregate information to analyze trends, administer the website, track user's movement, and gather broad demographic information for aggregate use. We may share this aggregate information with our corporate partners and contracted vendors to assist us in operating the website and to enable them to better understand Genentech's businesses.

Links to Third-Party Sites

This website may contain links to other websites on the Internet that are not under the control of nor maintained by Genentech. Such links do not constitute an endorsement by Genentech of those other websites, the content displayed therein, or the persons or entities associated therewith. You acknowledge that Genentech is providing these links to you only as a convenience, and you agree that Genentech is not responsible for the content of such websites. Your use of these other linked websites is subject to the respective terms of use and privacy policies located on the linked websites.


Genentech, and its third-party providers may employ procedural and technological security measures, consistent with industry practice. Such measures are reasonably designed to protect your personally identifiable information from loss, unauthorized access, disclosure, alteration or destruction. Genentech may use encryption, password protection, secure socket layers, internal restrictions and other security measures to help prevent unauthorized access to your personally identifiable information. However, you provide your information to us at your own risk. We cannot guarantee that your data will not be lost, accessed without authorization, disclosed, altered, or destroyed.

CALIFORNIA RESIDENTS | Supplemental Privacy Notice

If you are a California resident, you have the right to know how your personal information is being collected, used and disclosed. How Genentech collects, uses, and discloses personal identifying information for programs or services that link to this Privacy Policy is described in the Information Collection and Uses and the Sharing and Disclosure sections above. Genentech does not sell any personal identifying information collected under a program or service that link to this Privacy Policy.

You also have a right to request access to your personal information, to request to have your personal identifying information deleted, and the right to nondiscrimination if you exercise any of your rights. Should you exercise any of your privacy rights as a California resident, Genentech will not discriminate against you by offering you different pricing or products, or by providing you with a different level or quality of products. For detailed information on how to exercise your rights as a California resident with Genentech, please review our company’s privacy notice for California residents, available at the link below.

To review Genentech’s Supplemental Privacy Notice for California residents, click here.

Correction/Updating Personally Identifiable Information

Genentech is committed to respecting your right to access and correct your personal information. You can call 877-GENENTECH, and we will be happy to assist you with your request. You may also "opt-out" of receiving emails and other communications from us pertaining to the information and content of this website by using the unsubscribe feature included in the emails we send. If you have any questions about this online privacy policy or the information practices of our websites, you may contact Genentech by email at [email protected] or by mail at:

Contacting Genentech

Genentech, Inc. Attn: Privacy Office
Department 36M 1 DNA Way
South San Francisco, CA 94080

Important Safety Information & Indications

WHAT IS GAVRETO® (pralsetinib)?

GAVRETO is a prescription medicine used to treat certain cancers caused by abnormal rearranged during transfection (RET) gene in:

  • adults with non-small cell lung cancer (NSCLC) that has spread
  • adults and children 12 years of age and older with advanced medullary thyroid cancer (MTC) or MTC that has spread who require a medicine by mouth or injection (systemic therapy)
  • adults and children 12 years of age and older with advanced thyroid cancer or thyroid cancer that has spread who require a medicine by mouth or injection (systemic therapy) and who have received radioactive iodine and it did not work or is no longer working

Your healthcare provider will perform a test to make sure that GAVRETO is right for you.

GAVRETO was approved based on the percentage of patients whose tumor size shrank or disappeared after treatment and how long that response lasted. There are ongoing studies to confirm the benefit of GAVRETO.


GAVRETO may cause serious side effects, including

Lung Problems: GAVRETO may cause severe or life-threatening inflammation of the lungs during treatment, that can lead to death. Tell your healthcare provider right away if you have any new or worsening symptoms, including shortness of breath, cough, or fever.

High blood pressure (hypertension): High blood pressure is common with GAVRETO and may sometimes be severe. You should check your blood pressure regularly during treatment with GAVRETO. Tell your healthcare provider if you have increased blood pressure readings or get any symptoms of high blood pressure, including confusion, dizziness, headaches, chest pain or shortness of breath.

Liver problems: Liver problems (increased liver function blood test results) can happen during treatment with GAVRETO and may sometimes be serious. Your healthcare provider will do blood tests before and during treatment with GAVRETO to check you for liver problems. Tell your healthcare provider right away if you get any signs or symptoms of liver problem during treatment, including yellowing of your skin or the white part of your eyes (jaundice), loss of appetite, nausea or vomiting, dark “tea-colored” urine, pain on the upper right side of your stomach area, sleepiness, bleeding or bruising.

Bleeding problems: GAVRETO can cause bleeding which can be serious and cause death. Tell your healthcare provider if you have any signs or symptoms of bleeding during treatment, including vomiting blood or if your vomit looks like coffee-grounds, unusual vaginal bleeding, nose bleeds that happen often, pink or brown urine, drowsiness or difficulty being awakened, red or black (looks like tar) stools, confusion, coughing up blood or blood clots, headache, unusual bleeding or bruising of your skin, change in speech, or menstrual bleeding that is heavier than normal.

Tumor lysis syndrome (TLS): TLS is caused by a fast breakdown of cancer cells. TLS can cause you to have kidney failure and the need for dialysis treatment, an abnormal heartbeat, and may sometimes lead to hospitalization. Your healthcare provider may do blood tests to check you for TLS. You should stay well hydrated during treatment with GAVRETO. Call your healthcare provider or get emergency medical help right away if you develop any of these symptoms during treatment with GAVRETO: nausea, shortness of breath, vomiting, muscle cramps, weakness, seizures or swelling.

Risk of wound healing problems: Wounds may not heal properly during treatment with GAVRETO. Tell your healthcare provider if you plan to have any surgery before or during treatment with GAVRETO. You should not take GAVRETO for at least 5 days before surgery. Your healthcare provider should tell you when you may start taking GAVRETO again after surgery.

Before taking GAVRETO, tell your healthcare provider about all of your medical conditions, including if you:

  • have lung or breathing problems other than lung cancer.
  • have high blood pressure
  • have bleeding problems
  • plan to have surgery
  • are pregnant or plan to become pregnant. GAVRETO can harm your unborn baby.

    Females who are able to become pregnant:

    • Your healthcare provider will do a pregnancy test before you start GAVRETO.
    • Should use an effective form of non-hormonal birth control (contraception) during treatment with GAVRETO and for 2 weeks after the final dose of GAVRETO.
    • Birth control methods that contain hormones (such as birth control pills, injections or transdermal system patches) may not work as well during treatment with GAVRETO.
    • Talk to your healthcare provider about birth control methods that may be right for you during this time.
    • Tell your healthcare provider right away if you become pregnant or think you might be pregnant during treatment with GAVRETO.

    Males with female partners who are able to become pregnant should use effective birth control (contraception) during treatment and for 1 week after your final dose of GAVRETO.

  • are breastfeeding or plan to breastfeed. It is not known if GAVRETO passes into your breast milk. Do not breastfeed during treatment and for 1 week after your last dose of GAVRETO.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. GAVRETO may affect the way other medicines work, and other medicines may affect how GAVRETO works.

The most common side effects of GAVRETO include: constipation, decreased levels of phosphate in the blood, high blood pressure, decreased levels of calcium in the blood, tiredness, decreased levels of body salt (sodium) in the blood, muscle and joint pain, diarrhea, abnormal liver function blood tests, and decreased white blood cell, red blood cell, and platelet counts.

GAVRETO may affect fertility in males and females, which may affect your ability to have children. Talk to your healthcare provider if this is a concern for you.

These are not all of the possible side effects of GAVRETO. Call your doctor for medical advice about side effects. You are encouraged to report side effects to the FDA. Visit FDA MedWatch or call 1-800-FDA-1088. You may also report side effects to Genentech at 888-835-2555.

Please see the full Prescribing Information and Patient Information for GAVRETO.